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September 19, 2025The Journal of Applied Laboratory Medicine2 citations

The Hook Effect in Immunoglobulin A (IgA) Measurements: A Diagnostic Challenge—A Case Series

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AAAya AlmashadHHHoda A. Hagrass

Key Points

  • The hook effect may lead to inaccurate immunoglobulin A measurements, complicating clinical diagnosis.
  • Case examples demonstrate how the hook effect presents challenges in diagnosing certain conditions.
  • Inaccurate results due to the hook effect necessitate awareness among healthcare providers for proper interpretation.
  • Recognition of the hook effect can prevent diagnostic errors and improve patient management strategies.

Abstract

Journal Article The Hook Effect in Immunoglobulin A (IgA) Measurements: A Diagnostic Challenge—A Case Series Get access Aya Almashad, Aya Almashad Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, AR, United States Search for other works by this author on: Oxford Academic Google Scholar Hoda Hagrass Hoda Hagrass Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, AR, United States Address correspondence to this author at: Pathology Department, University of Arkansas for Medical Sciences, 4301 W. Markham St., Slot #502, Little Rock, AR 72205, United States. Tel 224-427-9748; e-mail: email protected, email protected. Search for other works by this author on: Oxford Academic Google Scholar The Journal of Applied Laboratory Medicine, jfaf132, https://doi.org/10.1093/jalm/jfaf132 Published: 16 September 2025 Article history Received: 06 May 2025 Accepted: 11 August 2025 Published: 16 September 2025

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Cite This Study

Almashad et al. (2025) studied this question.

synapsesocial.com/papers/68d469ba31b076d99fa65f8ahttps://doi.org/10.1093/jalm/jfaf132
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