Spectrum of Histopathological Lesions in Appendicectomy Specimens

Introduction : Acute appendicitis is the most common surgical emergency and appendicectomy is routinely performed worldwide. The peak incidence of acute appendicitis is seen in teens and early 20s. It is more common in males than females. Around 20% of patients who undergo appendicectomy are found not to have acute appendicitis on histopathological examination. Histopathological examination of the appendix allows diagnosis of the pathological lesions as well as additional pathologies which may not be evident intra-operatively that can impact the patient’s management. Materials & Methods : A cross sectional study of 2.5 year duration including 251 appendicectomy specimens in a Tertiary Care Centre was studied and reported on H&E stain sections to determine various histopathological lesions in appendicectomy specimens. Result : In present study, total 251 cases were studied, out of which 242 cases were non-neoplastic and 09 cases were neoplastic. The majority of the cases were in the middle age group. Clinically cases were operated for Acute Appendicitis but on histopathological examination we found maximum number of cases were of Lymphoid Hyperplasia (29.48%) followed by Healing appendicitis (23.50%) and 09 neoplastic cases were seen of Adenocarcinoma, Carcinoid syndrome and B-lymphoma each. Conclusion : Histopathological examination plays an important role in diagnosing and subtyping of appendicectomy specimens into various lesions and yield information about any neoplastic pathology present in cases with acute appendicitis. Therefore, the study was conducted to know the histopathological lesion in appendicectomy specimens.