September 20, 2025Journal of Pioneering Medical Science

Acute Oral Toxicity Assessment of Aqueous Extract of Streblus asper Root in Sprague Dawley Rats according to OECD 420 TG.

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Authors

MMMohd Hafiz MailNational Institutes of Biotechnology Malaysia ASAzman SeeniUniversiti Sains Malaysia FSFatemeh Shafie

Discussion

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Implication

Research reports no toxicity from aqueous extract of Streblus asper in Sprague Dawley rats, indicating safety. Findings suggest potential for medicinal plant applications in healthcare.

Key Points

No mortality or signs of toxicity were observed in Sprague Dawley rats after exposure to the aqueous extract.
The assessed LD50 of Streblus asper root exceeds 2000 mg/kg body weight, showing the extract’s high safety profile.
Monitoring included body weight, food consumption, and gross pathology over a 14-day period in the study.
Research supports the potential integration of medicinal plants into healthcare practices based on safety profiles.

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Mail et al. (2025) studied this question.

synapsesocial.com/papers/68d469ba31b076d99fa66218 https://doi.org/10.47310/jpms2025140808

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Implication

Research reports no toxicity from aqueous extract of Streblus asper in Sprague Dawley rats, indicating safety. Findings suggest potential for medicinal plant applications in healthcare.

Acute Oral Toxicity Assessment of Aqueous Extract of Streblus asper Root in Sprague Dawley Rats according to OECD 420 TG.

Discussion

Member takes

Implication

Key Points

Cite This Study

Acute Oral Toxicity Assessment of Aqueous Extract of Streblus asper Root in Sprague Dawley Rats according to OECD 420 TG.

Discussion

Member takes

Implication

Key Points

Cite This Study

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