What type of study is this?

This is a Cohort Study study (also classified as: Quantitative Study).

September 20, 2025Cancer Research

Abstract B023: Ovarian cancer tumor associated macrophages and tumor infiltrating lymphocytes in the stromal compartment associated with intrauterine device and oral contraception use

View Full Paper

Ask AI

Bookmark

Authors

JMJennifer M. MongioviBrigham and Women's Hospital RBRiddhi A. BabelMerck & Co., Inc., Rahway, NJ, USA (United States)ELEllie R. LeeHarvard University

Discussion

Member takes

Implication

Observational analysis reveals no significant associations between IUD, OC use, and immune profiles in ovarian tumors, suggesting further investigations are needed.

Key Points

There were no statistically significant associations found between contraception use and immune markers in the tumor microenvironment.
IUD use showed a higher odds (OR: 1.08) of CD3+CD8+ positivity, while OC use indicated lower odds (OR: 0.92).
Assessments were conducted using tissue microarrays and multiplex immunofluorescence to analyze tumor samples.
Further studies will explore potential modifiers like body mass index and endometriosis in relation to immune profiles.

Cite This Study

Mongiovi et al. (2025) studied this question.

synapsesocial.com/papers/68d469c131b076d99fa662db https://doi.org/10.1158/1538-7445.ovarian25-b023

View Full Paper

Ask AI

Bookmark

Implication

Observational analysis reveals no significant associations between IUD, OC use, and immune profiles in ovarian tumors, suggesting further investigations are needed.

Abstract B023: Ovarian cancer tumor associated macrophages and tumor infiltrating lymphocytes in the stromal compartment associated with intrauterine device and oral contraception use

Discussion

Member takes

Implication

Key Points

Cite This Study

Abstract B023: Ovarian cancer tumor associated macrophages and tumor infiltrating lymphocytes in the stromal compartment associated with intrauterine device and oral contraception use

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider