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September 20, 2025Applied SciencesOpen Access

Cymbopogon flexuosus and Eugenol Nanoemulsion: Formulation, Stability, Antimicrobial Efficacy, and In Vitro Safety Assessment

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Authors

FNFranciane Batista NunesRBRuth BarinLSLARISSA DA SILVA SILVEIRA

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Overview

Formulated nanoemulsion shows antimicrobial activity against pseudomonas aeruginosa and staphylococcus aureus, suggesting enhanced safety for topical use.

Key Points

  • NECE demonstrated bactericidal effects at 2.5 mg/mL against pseudomonas aeruginosa and 0.625 mg/mL against staphylococcus aureus.
  • The nanoemulsion formulation remained stable for 90 days at 4 °C while maintaining its antimicrobial activity.
  • NECE exhibited suitable physicochemical properties, including a mean size of less than 200 nm and PDI of less than 0.3.
  • Improved biocompatibility of the essential oil was observed in peripheral blood mononuclear cells.

Cite This Study

Nunes et al. (2025) studied this question.

synapsesocial.com/papers/68d469ce31b076d99fa669f4https://doi.org/10.3390/app151810214
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