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September 20, 2025Acta Marisiensis. Seria MedicaOpen Access

Innovative approach on monitoring methotrexate induced hepatotoxicity in psoriasis patients – A case report

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Authors

ASAna-Maria SanduOTOana Mirela TiucăRSRadu Alexandru Stan

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Overview

Case report shows safe Methotrexate use in a psoriasis patient with mild hepatotoxicity, suggesting FIB-4 can monitor liver risk.

Key Points

  • FIB-4 monitoring ensured safe Methotrexate use in a 44-year-old psoriasis patient, preventing severe liver damage.
  • During the first month of treatment, the patient developed mild hepatic steatosis but continued safe Methotrexate therapy.
  • Noninvasive FIB-4 effectively assessed liver fibrosis risk, aiding treatment adherence among psoriasis patients.
  • Close monitoring of liver function proved vital in managing Hepatotoxicity from Methotrexate therapy for psoriasis.

Cite This Study

Sandu et al. (2025) studied this question.

synapsesocial.com/papers/68d46aae31b076d99fa676b4https://doi.org/10.2478/amma-2025-0034
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