September 20, 2025Neuro-Oncology AdvancesOpen Access

Incidence and management of posterior fossa syndrome in children at a tertiary care hospital in Karachi: a 10-year retrospective cohort

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Discussion

Retrospective cohort analysis revealed 37.5% PFS incidence in pediatric patients, suggesting treatment options like zolpidem and therapy.

The incidence of posterior fossa syndrome following tumor resection is notably high, with 37.5% of patients affected, indicating the need for improved management.
Among 168 patients, 63 developed posterior fossa syndrome, showing higher incidence in males and those with fourth ventricular tumors, particularly medulloblastomas.
Patients who underwent speech therapy alongside zolpidem showed significant improvement in speech, suggesting effective therapeutic interventions for PFS.
This study highlights the significant risk factors associated with posterior fossa syndrome, underscoring the need for targeted approaches in treatment and management.

Mushtaq et al. (2025) studied this question.

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September 20, 2025Neuro-Oncology AdvancesOpen Access

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Authors

Retrospective cohort analysis revealed 37.5% PFS incidence in pediatric patients, suggesting treatment options like zolpidem and therapy.

The incidence of posterior fossa syndrome following tumor resection is notably high, with 37.5% of patients affected, indicating the need for improved management.
Among 168 patients, 63 developed posterior fossa syndrome, showing higher incidence in males and those with fourth ventricular tumors, particularly medulloblastomas.
Patients who underwent speech therapy alongside zolpidem showed significant improvement in speech, suggesting effective therapeutic interventions for PFS.
This study highlights the significant risk factors associated with posterior fossa syndrome, underscoring the need for targeted approaches in treatment and management.

Mushtaq et al. (2025) studied this question.

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