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September 20, 2025

Comparative Efficacy of 35 % Glycolic Acid Peel versus 4 % Retinol Peel in Melasma.

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Authors

TRTaku RiniRSRashmi SarkarBVBharati Verma

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Overview

Randomized controlled trial compared glycolic acid and retinol peels in melasma, revealing significant improvements indicating their efficacy.

Key Points

  • Both glycolic acid and retinol peels showed significant improvements in melasma pigmentation and quality of life measures.
  • Statistical analysis indicated improvements in mMASI and HI-MELASQOL with p-values < .001, with no significant differences between groups.
  • Dermoscopy effectively assessed response to treatment, supporting its usefulness in evaluating melasma treatment.
  • Mild adverse effects were reported more frequently in the retinol group, highlighting treatment tolerability differences.

Cite This Study

Rini et al. (2025) studied this question.

synapsesocial.com/papers/68d46abb31b076d99fa67f47https://doi.org/10.1097/dss.0000000000004858
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