PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
June 3, 2026Journal of Cutaneous and Aesthetic SurgeryOpen Access

Efficacy of glycolic acid peels in combination with topical therapy in common facial melanosis in skin of color: A randomized clinico-dermoscopic study

View Full Paper
Ask AI
Bookmark
Share

Authors

RSRashmi SarkarVMVibhu MendirattaABAyushman Bindal

Discussion

Loading...

Member takes

Overview

Randomized trial compares outcomes of topical therapy and glycolic acid peels in skin of color, suggesting combined treatment is more effective.

Key Points

  • The study aims to assess the effectiveness of glycolic acid peels combined with topical therapy in treating various forms of facial melanosis in patients with skin of color.
  • Randomized controlled trial with 120 patients divided into two groups.
  • Group 1 received topical therapy alone; Group 2 received topical therapy plus glycolic acid peels.
  • Evaluation based on clinical and dermoscopic scores over a 12-week period.
  • Significant decrease in clinical and dermoscopy scores for melasma and ADMH in Group 2 (p < 0.05).
  • PIH showed improved clinical scores, but dermoscopy results were not significant.
  • Combined treatment demonstrates additional benefits for facial melanosis.

Cite This Study

Sarkar et al. (2026) studied this question.

synapsesocial.com/papers/6a1fc40fdee9eb8c0dce5a59https://doi.org/10.25259/jcas_256_2025
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Comparative Efficacy of 35 % Glycolic Acid Peel versus 4 % Retinol Peel in Melasma.2025
  2. 2Comparison Between Efficacy of Serial Glycolic Acid Peel with Modified Kligman’s Regimen Vs Modified Kligman’s Regimen Alone in Epidermal Melasma2024
  3. 3Comparison Study Between Chemical Peeling with 70% Glycolic Acid and Intradermal Tranexamic Acid for the Treatment of Melasma2024 · 1 citations
  4. 4The Use of Medium‐Deep Peelings to Treat Melasma: A Case Series Study2025
  5. 5Combination of 20% Azelaic Acid Cream and 20% Salicylic Acid Peel Versus Azelaic Acid Cream Alone in the Treatment of Melasma Patients2025