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This is a Case-Control Study study.

Red blood cell morphology changes in peripheral blood smear of type 2 diabetes mellitus patients

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T2DM patients showed significantly lower packed cell volume compared to healthy controls, indicating hematological changes.
Hypochromasia was observed in 10% of T2DM patients, with anisocytosis seen in 6% of cases, pointing to morphological abnormalities.
Increased red cell distribution width was noted in younger females with T2DM, which may signify early vascular complications.
Simple hematological parameters should be considered for routine monitoring in diabetic patients to track potential complications.

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Case-control study examines RBC morphology and hematological parameters in T2DM patients, suggesting monitoring needs.

Martina et al. (2025) studied this question.

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