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September 21, 2025Journal of Pharmaceutical Research InternationalOpen Access

Comparative Efficacy of Preoperative Submucosal Dexamethasone Versus Methylprednisolone on Pain, Swelling and Trismus in Bilaterally Symmetrical Mandibular Third Molar Impaction Surgery

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Authors

MCMonica Roy ChandelGRGC RajkumarSNSantosh A. Nandimath

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Overview

Comparative analysis shows dexamethasone reduces pain and trismus, while methylprednisolone decreases swelling effectively.

Key Points

  • Dexamethasone led to greater reductions in post-operative pain and trismus compared to methylprednisolone.
  • Methylprednisolone significantly reduced post-operative swelling more than dexamethasone.
  • Results were based on a comparative analysis of 20 patients undergoing third molar surgery.
  • ANOVA statistical analysis was utilized to assess the efficacy of the two medications.

Cite This Study

Chandel et al. (2025) studied this question.

synapsesocial.com/papers/68d46ac231b076d99fa6825dhttps://doi.org/10.9734/jpri/2025/v37i97746
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effect of submucosal administration of dexamethasone on postoperative discomfort after third molar surgery2024
  2. 2Efficacy of Dexamethasone on Pain and Swelling Following Extraction of Impacted Mandibular Third Molars2025
  3. 3Efficacy of Submucosal versus Pterygomandibular Dexamethasone Injection in Surgical Extraction of the Impacted Lower Third Molar2024 · 1 citations
  4. 4“ Evaluation and Comparison of Locally Infiltrated Methylprednisolone and Intramuscularly Injected Methylprednisolone in controlling the postoperative sequelae of impacted mandibular third molar extraction”.2026
  5. 5Dexamethasone Injection on Postoperative Complications After Impacted Lower 3rd Molar Extraction2026