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This is a Experimental Study study.

September 21, 2025International Journal of Pharmaceutical and Bio-Medical ScienceOpen Access

Effect Of Hydromethanolic Mangifera Indica Stem Bark and Leaf Extracts on Motor Coordination and Grip Strength in ECT-Induced Seizure in Male Wistar Rats

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Authors

BOBuduka Justice OttoRivers State University IOIchechi Bright Owhorji COChibuike ObianduRivers State University

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Implication

This research shows that hydromethanolic extracts of Mangifera indica improve grip strength and motor coordination, indicating neuroprotective benefits in ECT-induced seizures.

Key Points

Hydromethanolic extracts of Mangifera indica significantly improved motor coordination and grip strength in ECT-induced seizure models.
Rats treated with MLE at 600 mg/kg showed robust improvements, reducing beam walk latency from 265.00 ± 62.85 s to 15.50 ± 6.37 s.
Control measures included ECT-only and ECT with diazepam, illustrating the extracts' efficacy compared to standard treatment.
These findings indicate the therapeutic potential of Mangifera indica extracts to mitigate neurocognitive side effects of ECT.

Cite This Study

Otto et al. (2025) studied this question.

synapsesocial.com/papers/68d46ac231b076d99fa683e1 https://doi.org/10.47191/ijpbms/v5-i9-02

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Implication

This research shows that hydromethanolic extracts of Mangifera indica improve grip strength and motor coordination, indicating neuroprotective benefits in ECT-induced seizures.

Effect Of Hydromethanolic Mangifera Indica Stem Bark and Leaf Extracts on Motor Coordination and Grip Strength in ECT-Induced Seizure in Male Wistar Rats

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Implication

Key Points

Cite This Study

Effect Of Hydromethanolic Mangifera Indica Stem Bark and Leaf Extracts on Motor Coordination and Grip Strength in ECT-Induced Seizure in Male Wistar Rats

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Implication

Key Points

Cite This Study

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