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September 21, 2025International Journal of Pharmaceutical and Bio-Medical ScienceOpen Access

The Effect of Hydromethanolic Extracts of Mangifera Indica Stem Bark and Leaf on Learning and Memory in Electroconvulsive Therapy-Induced Seizures in Male Wistar Rats

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Authors

BOBuduka Justice OttoRivers State University COChibuike ObianduRivers State University IOIchechi Bright OwhorjiRivers State University

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Implication

This research demonstrates that hydromethanolic extracts of Mangifera indica improve cognitive deficits in rats, highlighting their potential neuroprotective effects.

Key Points

Treatment with Mangifera indica extracts significantly reduced memory deficits caused by electroconvulsive therapy.
Rats receiving extracts showed improved escape latency (77.20 ± 2.28 s) compared to ECT-only group (257.40 ± 9.27 s).
Cognitive assessments utilized mazes and passive avoidance paradigms over four weeks to gauge learning effects.
These findings suggest that Mangifera indica extracts may offer neuroprotective benefits, warranting further investigation.

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Otto et al. (2025) studied this question.

synapsesocial.com/papers/68d46ac231b076d99fa683fb https://doi.org/10.47191/ijpbms/v5-i9-01

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Implication

This research demonstrates that hydromethanolic extracts of Mangifera indica improve cognitive deficits in rats, highlighting their potential neuroprotective effects.

The Effect of Hydromethanolic Extracts of Mangifera Indica Stem Bark and Leaf on Learning and Memory in Electroconvulsive Therapy-Induced Seizures in Male Wistar Rats

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Implication

Key Points

Cite This Study

The Effect of Hydromethanolic Extracts of Mangifera Indica Stem Bark and Leaf on Learning and Memory in Electroconvulsive Therapy-Induced Seizures in Male Wistar Rats

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Implication

Key Points

Cite This Study

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