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September 10, 2025International Journal of Advanced Research

Cognitive-Enhancing Effect of Ethyl Acetate Fraction of Erythrophleumivorense Stems Bark Against Ketamine-Induced Memory Impairment in Mice

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Authors

OWOlayemi K. WakeelOOOkoduwa J. OmoabhienaDKDamola O. Komolafe

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Overview

Observational study finds ethyl acetate from Erythrophleum ivorense improves memory impairment from ketamine, suggesting potential for Alzheimer's treatment.

Key Points

  • Erythrophleum ivorense reduced memory impairment in ketamine-treated mice, improving cognitive function.
  • In a passive avoidance test, the ethyl acetate fraction significantly decreased step through latency, indicating enhanced memory.
  • The study measured anti acetylcholinesterase and antioxidant activity in the brains of treated mice, confirming potential neuroprotective effects.
  • Findings suggest that herbal compounds like Erythrophleum ivorense may offer alternatives for managing Alzheimer's-related cognitive deficits.

Cite This Study

Wakeel et al. (2025) studied this question.

synapsesocial.com/papers/68c1c32754b1d3bfb60f1227https://doi.org/10.21474/ijar01/21379
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