This consensus document defines CRHM syndrome and highlights diagnostic criteria and management strategies, indicating interdisciplinary collaboration is essential.
Cardiovascular-renal-hepatic-metabolic (CRHM) syndrome is a complex and interrelated variety of diseases with common pathophysiological mechanisms. This interdisciplinary consensus document on CRHM syndrome provides a definition, diagnostic criteria, and describes its phenotypes and stages. Despite the growing prevalence of CRHM syndrome, unified strategies for patient management remain understudied. A paradigm shift in favor of CRHM syndrome makes it possible to withdraw from fragmented, organ-oriented management in favor of a more unified approach, facilitating collaboration between specialists and marking an advance in precision cardiometabolic medicine.
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Shlyakhto et al. (2025) studied this question.
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