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Evaluation of antidepressant activity of ethanolic extract of bacopa monnieri in swiss albino mice

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Ethanolic extract of bacopa monnieri improves depression symptoms in Swiss albino mice, suggesting potential therapeutic effects.

EEBM significantly reduced immobility time in mice, indicating strong antidepressant effects.
In the Forced Swim Test and Tail Suspension Test, EEBM outperformed the standard antidepressant imipramine.
Phytochemical analysis revealed glycosides and flavonoids in EEBM, contributing to its antidepressant activity.
Despite high dosing (2000 mg/kg), EEBM showed no mortality, indicating a favorable safety profile.

M et al. (2025) studied this question.

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