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This is a Experimental Study study.

September 21, 2025

A Multistep, One-Pot Bismuth-Mediated Radiohalogenation Method for Preparation of Radiopharmaceuticals for Imaging and Targeted Therapy.

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The method achieved radiochemical yields of 42-78% for three different labeled radiopharmaceuticals.
Regioselective bismuth-mediated radiohalogenation tolerates various functional groups on aromatic rings.
High radiochemical purity (>99%) was observed, indicating effectiveness in clinical applications.
The approach addresses the demand for efficient synthesis of radiohalogenated compounds in drug development.

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This method enables efficient radiohalogenation of arylboronates, suggesting new applications in radiopharmaceuticals.

Debnath et al. (2025) studied this question.

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