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September 21, 2025The International Journal of Maritime Engineering

An In-Silico Investigation of Marine Natural Products as Potential Inhibitors Against Non-Structural Protein 1 From Dengue Virus 2

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Authors

RSRanjay ShawGLA UniversityBPBharti PathakJamia HamdardVMV MittalChandigarh University

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Overview

In-silico analysis identifies marine natural products inhibiting NS1 in dengue virus, suggesting potential therapeutic roles.

Key Points

  • Three marine compounds demonstrated strong binding affinities to the glycosylation site of NS1.
  • In-silico assessments revealed favorable pharmacokinetic profiles with minimal cardiotoxicity risks.
  • Molecular docking simulations were used to evaluate the interaction potential of selected marine compounds.
  • Identified compounds could offer promising new avenues for dengue virus treatment development.

Cite This Study

Shaw et al. (2025) studied this question.

synapsesocial.com/papers/68d46cbf31b076d99fa68a9chttps://doi.org/10.5750/ijme.v167ia3(s).1695
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Also Consider

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  1. 1Marine Natural Products as Potential Inhibitors of NS2b/NS3-Protease of Dengue Virus: An In-Silico Approach2025
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