This research reveals common causes of squamous cell carcinoma in felines, suggesting early diagnosis is vital for effective treatment.
Squamous cell carcinoma (SCC) is a malignant cutaneous neoplasm that frequently occurs in felines, which shows distinct behavior compared to other species. Prolonged exposure to ultraviolet (UV) light appears to be one of the main etiological factors. Hypopigmented and sparsely haired areas are more commonly affected. Coat color is a known predisposing factor, with white-haired cats being more likely to develop the disease compared to those with pigmented coats. In terms of location, most lesions are found on the head, most commonly on the nasal planum, followed by the auricles and eyelids. Lesions may present in proliferative or erosive forms. Diagnostic suspicion is based on the animal’s history and the clinical characteristics of the lesions; however, cytological and histopathological examinations are necessary to confirm the diagnosis. Early diagnosis plays a critical role in the prognosis. Several treatment modalities are available for squamous cell carcinoma, including surgery, ionizing radiation, chemotherapy, photodynamic therapy, electrochemotherapy, and cryosurgery.
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Lopes et al. (2025) studied this question.
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