What type of study is this?

This is a Cohort Study study (also classified as: Quantitative Study, Experimental Study).

September 22, 2025PathogensOpen Access

Investigation of Intestinal Microbiota and Short-Chain Fatty Acids in Colorectal Cancer and Detection of Biomarkers

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Microbial alpha diversity is significantly lower in colorectal cancer patients compared to healthy controls, indicating ecological disruption.
Serum zonulin levels are elevated in CRC patients, suggesting a potential biomarker related to epithelial permeability.
Microbiota analysis utilized DNA isolation from stool, followed by sequencing and statistical diversity assessments.
Potential biomarkers for colorectal cancer include specific gut bacteria and elevated serum zonulin levels, highlighting targets for future research.

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This investigation reveals gut microbiota and biomarkers in colorectal cancer, suggesting their roles in disease progression.

Saylam et al. (2025) studied this question.

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