Prospective cohort study assesses the impact of diabetes and axial length on endothelial cell loss post-surgery.
Objective: To evaluate selected patient factors that affect endothelial cell loss 3 months followingphacoemulsification surgery.Methods: This was a prospective cohort study carried out at a single center, Eagle Eye and Laser Center, Nairobi,Kenya that has a Tomey 3000 specular microscope. All patients undergoing phacoemulsification surgery duringthe study period were included. The collected data was entered into Microsoft Excel and analyzed using SPSSResults: Average age was 65±12.327 with a M:F ratio of 1.2:1. Forty-one eyes of 33 patients were studied andshowed an overall endothelial cell loss of 7.2%. Diabetes was associated with more endothelial cell loss whilelonger axial length was associated with less endothelial cell loss.Conclusion: Phacoemulsification surgery is safe despite inevitable minimal loss in endothelial cells. Care shouldbe taken when operating on diabetic patients due to their susceptibility to more cell loss.
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Karagania et al. (2025) studied this question.
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