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September 22, 2025Complementary Medicine Research

Mechanisms of traditional chinese medicine in advanced gastric cancer: insights from meta-analysis and network pharmacology

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Authors

ZZZhenzheng ZhuYFYingmei FuQLQingyang Liu

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Overview

Meta-analysis reveals improved overall survival with traditional chinese medicine in advanced gastric cancer, suggesting new therapeutic targets.

Key Points

  • Traditional Chinese medicine significantly improves overall survival in advanced gastric cancer patients compared to chemotherapy alone.
  • Meta-analysis found TCM improved overall survival with a hazard ratio of 1.65, indicating a substantial benefit.
  • Integration of meta-analysis and network pharmacology helped identify core effective prescriptions and molecular targets.
  • Identified core genes including TP53 and EGFR can guide future research into therapeutic mechanisms and applications.

Cite This Study

Zhu et al. (2025) studied this question.

synapsesocial.com/papers/68d46fdc31b076d99fa6a54ahttps://doi.org/10.1159/000548562
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