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March 13, 2026Frontiers in OncologyOpen Access

Efficacy of traditional Chinese medicine combined with chemotherapy for gastric cancer and precancerous gastric lesions: a systematic review and meta-analysis

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Authors

XLXiao LiangLYLiu YangSYShuaiqi Yuan

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Overview

Systematic review reveals improved outcomes for gastric cancer with TCM and chemotherapy, suggesting enhanced treatment options.

Key Points

  • To analyze the effects of combining Traditional Chinese Medicine with chemotherapy in treating gastric cancer and precancerous lesions.
  • Conducted systematic review and meta-analysis using PubMed, Cochrane Library, and Embase.
  • Evaluated primary outcomes such as complete response rates, disease control rates, and quality of life.
  • Used random effect models for statistical analysis, including standardized mean differences and odds ratios.
  • Assessed publication bias through funnel plots and regression tests.
  • Meta-analysis included five studies with diverse outcomes.
  • Combined therapy showed significant improvement in complete response rates with an odds ratio of 4.20.
  • Quality of life scores indicated high standardized mean differences, suggesting benefits from TCM.
  • Statistical tests indicated considerable heterogeneity among outcome measures.

Cite This Study

Liang et al. (2026) studied this question.

synapsesocial.com/papers/69b3aaa802a1e69014ccb68ahttps://doi.org/10.3389/fonc.2026.1781660
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