September 23, 2025European Journal of EndocrinologyOpen Access

OC51 - Effects of modified release hydrocortisone on reproductive function in males with congenital adrenal hyperplasia. Insights from CALLIOPE: a multicenter, prospective study

View Full Paper

Ask AI

Bookmark

Authors

DFDavide FerrariSapienza University of Rome CSChiara SimeoliIstituto Nazionale di Fisica Nucleare, Sezione di Napoli LALorenzo ArcolesseSapienza University of Rome

Discussion

Member takes

Implication

Prospective analysis shows improved semen parameters in adult males with CAH using modified-release hydrocortisone, suggesting potential benefits for reproductive health.

Key Points

A 72.3% increase in sperm concentration was observed after modified-release hydrocortisone treatment, highlighting its positive effect.
20 out of 32 male patients showed detectable TARTs, indicating significant prevalence in this population.
Participants underwent assessments before and after approximately 6 months of treatment with modified-release hydrocortisone.
Further research is needed to validate findings and assess long-term efficacy in larger cohorts.

Cite This Study

Ferrari et al. (2025) studied this question.

synapsesocial.com/papers/68d4724f31b076d99fa6ad0d https://doi.org/10.1093/ejendo/lvaf168.093

View Full Paper

Ask AI

Bookmark

Implication

Prospective analysis shows improved semen parameters in adult males with CAH using modified-release hydrocortisone, suggesting potential benefits for reproductive health.

OC51 - Effects of modified release hydrocortisone on reproductive function in males with congenital adrenal hyperplasia. Insights from CALLIOPE: a multicenter, prospective study

Discussion

Member takes

Implication

Key Points

Cite This Study

OC51 - Effects of modified release hydrocortisone on reproductive function in males with congenital adrenal hyperplasia. Insights from CALLIOPE: a multicenter, prospective study

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider