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September 23, 2025Journal of Applied Polymer Science

3D Printed PLA Scaffolds Modified With Chitosan‐Based Electrospun Nanofibers for Biomimetic Mineralization and Antimicrobial Efficacy

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Authors

KGKajal GoswamiMGMegha GargPSPankaj Sharma

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Overview

This work demonstrates effective hydroxyapatite deposition and antimicrobial activity in PLA scaffolds, highlighting the role of chitosan.

Key Points

  • The modified PLA scaffolds showed significant enhancement in hydroxyapatite deposition.
  • Hydroxyapatite crystals formed on scaffolds have a flower-like morphology, confirming effective biomineralization.
  • Chitosan nanofibers enhanced the antimicrobial activity against Staphylococcus aureus and Escherichia coli.
  • The study provides insights into using 3D printed PLA scaffolds for potential applications in bone tissue regeneration.

Cite This Study

Goswami et al. (2025) studied this question.

synapsesocial.com/papers/68d4724f31b076d99fa6ad71https://doi.org/10.1002/app.58022
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  5. 5HAp/PLGA/Chitosan Scaffolds Fabricated by Freeze-Drying and 3D Printing for Bone Regeneration: In Vitro Evaluation and Finite Element Analysis2026