What question did this study set out to answer?

To develop enhanced 3D-printed polylactic acid scaffolds for improved bone regeneration through surface modification.

Extracellular Matrix-InspiredElectrospun Nanofiber-Coated3D-Printed Polylactic Acid Scaffolds for Bone Regeneration

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Randomized trial demonstrates enhanced bone regeneration in scaffolds, suggesting a novel biomimetic approach.

To develop enhanced 3D-printed polylactic acid scaffolds for improved bone regeneration through surface modification.
3D-printed PLA scaffolds treated with oxygen plasma to enhance hydrophilicity.
Electrospinning of alginate/PEO nanofibers with magnesium phosphate nanoparticles used to coat the scaffolds.
In vitro cell studies conducted to assess cell attachment and proliferation.
Cell attachment and proliferation significantly improved in Alg/MP/OPLA/CaP scaffold compared to control (specific rates not provided).
Enhanced osteogenic activity in the presence of magnesium phosphate nanoparticles noted during in vitro studies.
Calcium phosphate deposition confirmed through ATR-FTIR, XRD, and FE-SEM analysis.

Goswami et al. (2026) studied this question.

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