Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 23, 2025Asian Pacific Journal of Tropical BiomedicineOpen Access

Naringenin nanoparticles show anti-angiogenic activity in HUVECs and a chick chorioallantoic membrane model and anticancer activity in MCF-7 cells

View Full Paper
Ask AI
Bookmark
Share

Authors

SYSanthosh Kumar YasamKarpagam Academy of Higher EducationGSGowtham Kumar SubbarajChettinad Academy of Research and EducationDVD. Danis VijayChettinad Academy of Research and Education

Discussion

Loading...

Member takes

Overview

Analysis confirms anti-angiogenic effects in HUVECs and anticancer effects in MCF-7 cells, indicating significant potential for cancer therapy.

Key Points

  • Naringenin nanoparticles significantly reduced cell viability in both HUVEC and MCF-7 cells, indicating strong anticancer activity.
  • Molecular docking confirmed effective binding of naringenin to vascular endothelial growth factor, enhancing its therapeutic promise.
  • Naringenin nanoparticles exhibited significant inhibition of migration and downregulated pro-angiogenic markers in cell cultures.
  • Chick chorioallantoic membrane assays demonstrated reduced blood vessel density, highlighting the anti-angiogenic potential of naringenin nanoparticles.

Cite This Study

Yasam et al. (2025) studied this question.

synapsesocial.com/papers/68d4726431b076d99fa6b74fhttps://doi.org/10.4103/apjtb.apjtb_178_25
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1PROCHECK: a program to check the stereochemical quality of protein structures1993 · 24,840 citations
  2. 2Quercetin Suppresses Twist to Induce Apoptosis in MCF-7 Breast Cancer Cells2015 · 211 citations
  3. 3Neuro-protective effects of nano-formulated hesperetin in a traumatic brain injury model ofDanio rerio2020 · 24 citations
  4. 4In vitro synergistic effect of hesperidin and doxorubicin downregulates epithelial-mesenchymal transition in highly metastatic breast cancer cells2023 · 40 citations