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September 23, 2025Veterinary Dermatology

Clinical, Histopathological and Molecular Characterisation of Canine Epitheliotropic Cutaneous T‐Cell Lymphoma With Cytotoxic Interface Dermatitis: A Retrospective Case Series

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Authors

LSLynn SmithFBFrane BanovićMPMarlene S Pariser

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Overview

Case series highlights unique features of cytotoxic dermatitis in eCTCL, emphasizing immunohistochemical findings.

Key Points

  • All six canine cases displayed a cytotoxic pattern distinct from other dermatitis diseases.
  • Histopathological examination showed strong CD3+ T-cell presence and apoptotic keratinocytes in all cases.
  • Immunohistochemical analysis and clonal testing confirmed the diagnosis and response to treatment.
  • Further research may help distinguish this variant from other cutaneous conditions in veterinary dermatology.

Cite This Study

Smith et al. (2025) studied this question.

synapsesocial.com/papers/68d4739d31b076d99fa6bc65https://doi.org/10.1111/vde.70029
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  3. 3Comprehensive phenotypic and clonality analysis of intraepithelial lymphocytes of intestinal T-cell lymphoma and chronic enteropathy in dogs2026
  4. 4Multifocal non-epitheliotrophic cutaneous B-cell Lymphoma in a dog: cytologic, histopathologic, immunophenotypic, and molecular findings2026
  5. 5Histopathological and Ultrastructural Study of a Canine Langerhans Cell Tumour (Canine Cutaneous Histiocytoma)2024 · 1 citations