Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 23, 2025Brazilian Journal of BiologyOpen Access

Neonatal malnutrition and macrophage in Candida albicans infection

View Full Paper
Ask AI
Bookmark
Share

Authors

NMNatália Gomes de MoraisTCThacianna Barreto da CostaVPValéria Rêgo Alves Pereira

Discussion

Loading...

Member takes

Overview

This study demonstrates altered immune responses in malnourished rats exposed to Candida albicans, suggesting critical effects on immunity.

Key Points

  • Malnutrition during the neonatal period impaired immune responses to Candida albicans infection.
  • Macrophages from malnourished rats showed lower expression of key immune mediators like TLR-9 and IL-18.
  • The study used male Wistar rats divided into malnourished and nourished groups with differing protein intake.
  • Findings indicate that neonatal malnutrition leads to diminished body growth and weakened defense mechanisms.

Cite This Study

Morais et al. (2025) studied this question.

synapsesocial.com/papers/68d473a631b076d99fa6becahttps://doi.org/10.1590/1519-6984.284465
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Early-life Fungal Colonization Reveals Stage-specific Immune Regulation in the Oral Mucosa 22411712026
  2. 2Malnutrition in Healthy Individuals Results in Increased Mixed Cytokine Profiles, Altered Neutrophil Subsets and Function2016 · 77 citations
  3. 3Role of carbon and nitrogen assimilation in Candida albicans survival and virulence2024 · 2 citations
  4. 4Effects of Moderate Malnutrition during Pregnancy on Neonatal Immunity to Malaria 23692025
  5. 5Neonatal Candidaemia — A Retrospective, Observational Study with Comparison between Albicans and Non-albicans Candida among Low Birth Weight and Normal Birth Weight Babies2026