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September 23, 2025Metabolism and Target Organ DamageOpen Access

Association of exposure to phenols, pesticides, and phthalates with hepatic steatosis and MASLD in adolescents: the potential role of inflammation and lifestyle factors

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Authors

XYXiaodie YaoCTCai TangLYLi Yu

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Overview

Observational analysis reveals associations of chemicals with MASLD in adolescents, indicating inflammation's role.

Key Points

  • Exposure to phenols, pesticides, and phthalates is linked to higher rates of hepatic steatosis and MASLD in adolescents.
  • Among 2,163 adolescents, 22.7% were diagnosed with MASLD, with bisphenol A as a key contributor.
  • Analysis utilized generalized linear models, weighted quantile sum regression, and kernel machine regression approaches.
  • Reducing sedentary behavior and increasing physical activity may lower the risk of MASLD related to chemical exposure.

Cite This Study

Yao et al. (2025) studied this question.

synapsesocial.com/papers/68d473bb31b076d99fa6c90ehttps://doi.org/10.20517/mtod.2025.103
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