Value of Radiotherapy in Complex Treatment of Locally Advanced Pancreatic Cancer

Purpose: To familiarize radiation oncologists and specialists of related specialties with various aspects of a promising, comprehensive approach to patients with locally advanced pancreatic cancer. Materials and methods: The review includes data from domestic and foreign articles found in PubMed/MEDLINE, as well as a clinical case. Results: As a clinical example, patients with locally advanced pancreatic cancer who received chemotherapy followed by radiation therapy are presented, and the immediate results of treatment are demonstrated. Conclusions: Despite the predominant role of chemotherapy and surgery in the treatment of pancreatic cancer, radiation therapy still plays an important role in the comprehensive treatment of this disease as a method that improves local control in resectable, borderline resectable, locally advanced, and recurrent pancreatic cancer. However, there is a lack of data on the methods, target volume determination, and fractionation schemes.