Role and Place of Radiation Therapy in Complex Treatment of Patients with de novo Metastatic Breast Cancer. Literature Review and Clinical Observations

According to state-of-art clinical guidelines, the leading method of treatment for de novo metastatic breast cancer is systemic therapy. However, the possibility and feasibility of performing local methods in treating the primary lesion in the above mentioned patients, such as surgery and radiation therapy, is currently being actively studied. This article provides a review of modern literature data related to the issues of external beam radiation therapy in patients with de novo metastatic breast cancer and presents our own clinical observations.