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September 23, 2025Open Access

Comparing Efficacy and Safety of Endovascular Thrombectomy Versus Best Medical Management in Acute Isolated Posterior Cerebral Artery Occlusion Stroke: A Systematic Review and Meta-analysis

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Authors

MWMuhammad Hassan WaseemZAZain ul AbideenAWAiman Waheed

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Overview

Meta-analysis reveals endovascular thrombectomy offers improved neurological outcomes, but increases risks of symptomatic intracranial hemorrhage and mortality.

Key Points

  • Endovascular thrombectomy shows significant early neurological improvement compared to best medical management.
  • Rates of symptomatic intracranial hemorrhage and mortality are significantly higher with endovascular thrombectomy.
  • Visual field normalization is comparable between endovascular thrombectomy and best medical management.
  • Functional outcomes show no significant differences between endovascular thrombectomy and best medical management.

Cite This Study

Waseem et al. (2025) studied this question.

synapsesocial.com/papers/68d4759931b076d99fa6da70https://doi.org/10.21203/rs.3.rs-7312011/v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Endovascular Thrombectomy for Acute Ischemic Stroke Due to Distal Medium Vessel Occlusion: A Systematic Review and Meta-Analysis2026
  2. 2Endovascular thrombectomy for acute ischemic stroke with a large infarct area: an updated systematic review and meta-analysis of randomized controlled trials2024
  3. 3ABSTRACT NUMBER: ESOC2026A2339 EXPERIENCE FROM A PORTUGUESE TERTIARY HOSPITAL IN ISOLATED POSTERIOR CEREBRAL ARTERY OCCLUSION: MEDICAL MANAGEMENT OR ENDOVASCULAR THERAPY2026
  4. 4Endovascular Thrombectomy Versus Intravenous Thrombolysis of Posterior Cerebral Artery Occlusion Stroke2024 · 32 citations
  5. 5Endovascular treatment in acute ischemic stroke patients with pre-stroke disability: A systematic review and meta-analysis2026