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September 23, 2025Open Access

Can Large Language Models Reliably Interpret Radiology Reports? A Systematic Evaluation for Tumor Progression Classification

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Authors

VPValentin PohyerInsermCMConstance de Margerie‐MellonInsermLPLaetitia PerronneNorthwestern University

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Overview

Systematic evaluation reveals large language models outperform BERT in classifying tumor progression, indicating significant potential for clinical data processing.

Key Points

  • Large language models demonstrated superior performance in classifying tumor progression from radiology reports, with 310 cases analyzed.
  • Models were tested on different architectures and prompting strategies, achieving better results than traditional rule-based and BERT-based methods.
  • The evaluation highlighted a trade-off between computational resources and the need for human annotations, affecting cost and development time.
  • Selected models showed better efficiency than fine-tuned BERT, suggesting paths for optimizing the use of clinical text data.

Cite This Study

Pohyer et al. (2025) studied this question.

synapsesocial.com/papers/68d4759931b076d99fa6da91https://doi.org/10.21203/rs.3.rs-7630430/v1
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