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September 23, 2025Synfacts

Enantioconvergent Reductive Cross-Coupling of Benzylic Alcohols with Alkenyl Bromides under Nickel Catalysis

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This process ensures high enantioselectivity in synthesizing complex molecules from benzylic alcohols.
The coupling reaction yields enantiomers efficiently, highlighting the versatility of nickel as a catalyst.
This methodology is beneficial for organic reactions, specifically in creating diverse alkenyl compounds.
The use of nickel catalysis presents an eco-friendly alternative to traditional methods, potentially reducing waste.

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Cross-coupling reacts benzylic alcohols with alkenyl bromides under nickel catalysis, indicating efficiency in enantioconvergent synthesis.

Keywords alcohols - alkenyl bromides - cross-electrophile coupling - nickel catalysis

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Cross-coupling reacts benzylic alcohols with alkenyl bromides under nickel catalysis, indicating efficiency in enantioconvergent synthesis.

Keywords alcohols - alkenyl bromides - cross-electrophile coupling - nickel catalysis