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September 23, 2025Annals of PIMS-Shaheed Zulfiqar Ali Bhutto Medical University

Frequency of Causes of Unconjugated Hyperbilirubinemia Leading to Exchange Transfusion

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Authors

MNMunazza NazirSKSharaf KhanKIKamal Kharazzi Ilyas

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Overview

Descriptive cross-sectional study identifies Rh and ABO incompatibility as leading causes of jaundice in neonates, highlighting clinical implications.

Key Points

  • Rh incompatibility was the most common cause of neonatal jaundice requiring exchange transfusion, affecting 55% of cases.
  • Among 110 neonates studied, 73 (66.36%) were male, indicating a higher prevalence in males compared to females.
  • Clinical assessments included demographic details and interpretations of blood group compatibility to determine causes of hyperbilirubinemia.
  • Findings support the need for prompt identification of jaundice causes, as Rh incompatibility significantly impacts treatment strategies.

Cite This Study

Nazir et al. (2024) studied this question.

synapsesocial.com/papers/68d4765531b076d99fa6e86bhttps://doi.org/10.48036/apims.v20i4.1026
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Risk factors for exchange transfusion in neonates with unconjugated hyperbilirubinemia: A tertiary care hospital study.2024
  2. 2Exaggerated Physiological Jaundice and Exchange Transfusion in Neonates.2025
  3. 3Developmental outcome of neonates underwent exchange transfusion due to hyperbilirubinemia: A single-center experience2024 · 1 citations
  4. 4A Case Report on Exchange Transfusion in New Born Infant with Neonatal Jaundice and Rh Incompatibility2025
  5. 5Prevalent causes and outcomes of unconjugated hyperbilirubinemia in neonates2025