Recent Development of Organ-on-a-Chips for Biomedical Applications

Coronavirus disease (COVID-19) pandemic was occurred and continuously getting worse on 2020. A first patient of COVID-19 was reported on Wuhan City, China on Dec 2019. There is no vaccines and target drugs for COVID-19 because it is a new evolved infectious disease. The corona virus of COVID-19 was rapid spread to many peoples and nations within several months. World Health Organization (WHO) announced that 216 countries or areas in the world was infected by COVID-19 with 16,523,815 confirmed cases and 655,112 confirmed deaths on 29 July 2020 [1]. Although vaccines and drugs for COVID-19 are highly needed, developing vaccines and new drugs require high cost and long time. Recently organ-on-a-chip or human-on-a-chip was suggested a new test method to reduce cost and time for developing a new drug [2,3]. Especially these organ-on-a-chip can replace an animal in a non-clinical test [2,3]. In this review, recent developed organ-on-a-chips and their various applications are explained