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Systematic review shows triptolide impacts amyloid-beta accumulation and neuroinflammation in AD models, suggesting therapeutic potential.
Aim This study aims to systematically evaluate and synthesize preclinical evidence on the neuroprotective effects of Triptolide (Tri) in Alzheimer's disease (AD) models, focusing on its impact on amyloid-beta accumulation, synaptic dysfunction, neuroinflammation, oxidative stress, autophagy, and apoptosis.
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Shami et al. (2025) studied this question.
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