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September 26, 2025FoodsOpen Access

Enhanced Bioactive Peptide Release from Pre-Hydrolysed Pea Protein: Impact of Pepsin Digestion on Antidiabetic and Antihypertensive Functions

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Authors

AEArig ElbiraUniversity of LeedsAHAlan Javier Hernández‐ÁlvarezUniversity of LeedsCBChristine BöschUniversity of Leeds

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Implication

This study demonstrates that pepsin digestion significantly increases bioactivity in pea protein, suggesting potential metabolic health benefits.

Key Points

  • Pepsin digestion increased hydrolysis in pre-hydrolysed pea protein to 64%, enhancing bioactive peptide release.
  • Inhibition of α-amylase and α-glucosidase reached 44.5% and 54%, respectively, with ACE inhibition at 95%.
  • Ultrafiltration enriched peptides under 10 kDa, showcasing improved metabolic enzyme inhibition from pre-hydrolysed samples.
  • Findings underscore the importance of enzymatic hydrolysis for developing functional ingredients in diabetes and cardiovascular health.

Cite This Study

Elbira et al. (2025) studied this question.

synapsesocial.com/papers/68d6c68eb1249cec298b2e02https://doi.org/10.3390/foods14193306
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Also Consider

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