The effectiveness of treatment of chronic generalized periodontitis of mild severity using antimicrobial and pyle therapy

Relevance. The comparative effectiveness of antimicrobial therapy and light pyre therapy in the treatment of chronic generalized periodontitis has not been sufficiently studied. Further development and implementation of methods for the treatment of periodontal diseases with minimal drug load is necessary. Objective. To compare the effectiveness of antimicrobial and pyler-therapy in the treatment of mild chronic generalized periodontitis. Materials and methods. The treatment was carried out in two groups of patients (40 people each), aged from 30 to 50 years (44 women and 36 men). In the first group, Dentameth gel containing metronidazole and chlorhexidine bigluconate was used. In the second group, piper therapy was performed using the Bioptron Pro-1 device. The hygiene index and periodontal index were calculated, and the activity of neutrophilic leukocytes was determined before therapy, one, three, and six months after treatment. Results. Antimicrobial therapy and pyler therapy have a significant positive effect on the periodontal condition of patients for three months (p<0.05). The values of the periodontal indices obtained after six months allow us to consider the treatment performed insufficient. The activity of myeloperoxidase and the number of cationic proteins intracellularly in neutrophilic leukocytes increases during the month, and decreases by three and six months, which is directly correlated with the clinical symptoms. Conclusions. In the treatment of chronic generalized periodontitis, antimicrobial therapy and pyler-therapy show the same high efficacy, which persists for three months. When using only one of these methods as the basic active periodontal treatment, supportive periodontal therapy is indicated after three months.