Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
August 1, 2025Open Access

The Effects Of Amoxicillin And Metronidazole On Patients With Untreated Stage Iii Grade C Generalized Periodonti-tis: A Prospective Randomized Clinical Trial With 6- And 12-month Follow-ups

View Full Paper
Ask AI
Bookmark
Share

Authors

BSBarbora StenchlákováMBMartin BacinskyMGMarian Grendár

Discussion

Loading...

Member takes

Overview

Prospective trial shows lower probing depth with antibiotics in stage III grade C periodontitis, suggesting improved outcomes.

Key Points

  • Adjunctive amoxicillin and metronidazole reduced probing depth significantly at 6 months in periodontitis patients.
  • Changes in clinical attachment loss and bleeding on probing did not show significant differences between groups.
  • The study followed 40 patients over 12 months, measuring various periodontal parameters.
  • Further research is needed to explore the long-term effects of antibiotics on clinical attachment loss.

Cite This Study

Stenchláková et al. (2025) studied this question.

synapsesocial.com/papers/689a0c65e6551bb0af8cfb50https://doi.org/10.20944/preprints202507.2434.v1
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Adjunctive Systemic Antimicrobials in the Treatment of Generalized Stage III, Grade C Periodontitis: A Triple-Blind, Randomized Placebo-Controlled Trial2026
  2. 2Comparative Study of Systemic vs. Local Antibiotics with Subgingival Instrumentation in Stage III–IV Periodontitis: A Retrospective Analysis2024 · 10 citations
  3. 3The Effect of Adjunctive Systemic Antibiotics on the Outcomes of Non‐Surgical Periodontal Therapy: A Retrospective Cohort Study2026 · 1 citations
  4. 4Efficacy of Periodontal Surgery With Adjunctive Systemic Antimicrobials in Patients Harbouring <scp> <i>Porphyromonas gingivalis</i> </scp> : A 48‐Month Randomised Clinical Trial2025
  5. 5Immunomodulators, associated or not with systemic antibiotics, to treat periodontitis: A 1‐year multicenter, placebo‐controlled, double‐blind, randomized clinical trial2026