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September 26, 2025RSC AdvancesOpen Access

One-step electrochemical aptasensor for lactate detection in athlete training using AuPt NPs and PEI-rGO composite with Na⁺-dependent DNAzyme

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Sensitive lactate detection achieved using an electrochemical aptasensor with Na+-dependent DNAzyme.
Results indicate detection limits suitable for athlete training, demonstrating practical application potential.
The method utilizes a composite of AuPt NPs and PEI-rGO to enhance sensor performance and sensitivity.
Findings support the viability of a wearable monitoring system for athletes’ lactate levels.

Aptasensor shows sensitive lactate detection in athlete sweat, highlighting the role of Na+-dependent DNAzyme.

Illustration of an aptasensor based on PEI-rGO and Na + -dependent DNAzyme for sensitive detection of lactate (LA) in athlete sweat.

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Han et al. (2025) studied this question.

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Aptasensor shows sensitive lactate detection in athlete sweat, highlighting the role of Na+-dependent DNAzyme.

Illustration of an aptasensor based on PEI-rGO and Na + -dependent DNAzyme for sensitive detection of lactate (LA) in athlete sweat.