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September 24, 2025World Journal of Gastrointestinal Surgery

Diagnostic significance of fluorine-18-fluorodeoxyglucose-positron emission tomography/computed tomography in differentiating Edmondson grade II and III hepatocellular carcinoma

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Authors

XNXiaobo NiuInner Mongolia People's HospitalYLYanpeng LiXinjiang Medical UniversityFCFang-Fang ChaoFirst Affiliated Hospital of Zhengzhou University

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Implication

Observational analysis reveals metabolic parameters differentiate grades in hepatocellular carcinoma, suggesting potential in prognostic assessment.

Key Points

  • SUVmax significantly distinguishes between Edmondson grade II and III hepatocellular carcinoma, indicating its diagnostic importance.
  • The observed sensitivity and specificity for identifying grade III HCC with an SUVmax cut-off of 10.95 were 66.7% and 100%, respectively.
  • Retrospective analysis of 32 patients with solitary hepatocellular carcinoma assessed metabolic parameters using 18F-FDG PET/CT imaging.
  • These findings highlight the relevance of Ki67 expression alongside imaging biomarkers for prognostic evaluations in HCC.

Cite This Study

Niu et al. (2025) studied this question.

synapsesocial.com/papers/68d6d8548b2b6861e4c3e729https://doi.org/10.4240/wjgs.v17.i9.107301
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