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September 10, 2025Quantitative Imaging in Medicine and SurgeryOpen Access

Correlation between dual-time-point 18F-FDG PET/CT imaging and pathological grade in hepatocellular carcinoma

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Authors

DXDi XiaoZWZhao WangLZLihua Zhao

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Overview

Retrospective analysis demonstrates significant correlations of DTP 18F-FDG PET/CT metrics with histological grades in HCC, indicating enhanced diagnostic capability.

Key Points

  • Delayed 18F-FDG PET/CT imaging enhances tumor visualization and correlates positively with histological grades of HCC.
  • Significant differences in SUVmax (3.50 vs. 3.10, P=0.001) and SUVratio (1.89 vs. 1.67, P<0.001) were noted between delayed and early imaging.
  • The study retrospectively analyzed data from 40 HCC patients, focusing on SUVmax, SUVavg, and SUVratio correlations with histological grades.
  • These results highlight the clinical utility of dual-time-point imaging in non-invasive assessment and treatment planning for HCC.

Cite This Study

Xiao et al. (2025) studied this question.

synapsesocial.com/papers/68c1a5f254b1d3bfb60df787https://doi.org/10.21037/qims-2025-196
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Integrated Dedicated Liver 2025
  2. 2Prognostic Value of 18F-FDG and 18F-FEC Uptake in Hepatocellular Carcinoma Using Contrast-Enhanced Integrated PET/MRI: Correlation with Histology and Survival2026
  3. 3Diagnostic significance of fluorine-18-fluorodeoxyglucose-positron emission tomography/computed tomography in differentiating Edmondson grade II and III hepatocellular carcinoma2025
  4. 4High standard uptake value on FDG-PET/CT of the primary lesion of hepatocellular carcinoma correlates with early recurrence after curative resection2024
  5. 5Dual-tracer [18F]F-FDG and [18F]F-FAPI-04 PET/CT for predicting tumor aggressiveness and prognosis in hepatocellular carcinoma2026