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September 24, 2025Open Access

Risk of vaso-occlusive crisis requiring hospitalization in sickle cell disease patients in Brazil: retrospective cohort study of real-world data

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Authors

VBV M Rocha BarrosASAna Cristina Silva‐PintoPMPatrícia Moura

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Overview

Retrospective cohort study shows high incidence of vaso-occlusive crises in Brazilian sickle cell disease patients, indicating significant healthcare resource utilization.

Key Points

  • During a 3-year follow-up, 59.4% of participants experienced vaso-occlusive crises requiring hospitalization.
  • The incidence rate of vaso-occlusive crises was reported as 812 events per 1000 person-years among the cohort.
  • The study assessed healthcare resource utilization, including treatments, testing, and hospitalizations in sickle cell disease patients.
  • Sickle cell disease in Brazil continues to drive substantial healthcare costs, highlighting the need for improved management strategies.

Cite This Study

Barros et al. (2025) studied this question.

synapsesocial.com/papers/68d6d8978b2b6861e4c3ec6ahttps://doi.org/10.21203/rs.3.rs-7576339/v1
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Also Consider

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  5. 5How we prevent and manage infection in sickle cell disease2015 · 44 citations