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September 24, 2025Frontiers in Reproductive HealthOpen Access

Effects of in vitro fertilization and intracytoplasmic sperm injection treatment on female patients' perinatal mental health: systematic review and meta-analysis

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Authors

HNHana NěmcováTBTereza BlaskovaAHAnna Hořáková

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Overview

Systematic review evaluates mental health outcomes of IVF and ICSI patients, revealing significant anxiety impact.

Key Points

  • Women undergoing IVF showed significantly higher anxiety levels compared to those conceiving naturally.
  • Five studies assessed depression symptoms, indicating no significant difference between IVF and spontaneous conception groups.
  • The systematic review included 44 studies with a total of 858,966 participants, highlighting the need for further research.
  • Healthcare providers should address the mental health impacts of IVF/ICSI, especially related to anxiety symptoms.

Cite This Study

Němcová et al. (2025) studied this question.

synapsesocial.com/papers/68d6d8978b2b6861e4c3eda2https://doi.org/10.3389/frph.2025.1668831
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Emotional Impact of In Vitro Fertilization (IVF): Anxiety, Depression, and Their Relationship with Pregnancy Outcomes2025
  2. 2Women’s In Vitro Fertilization Treatment Experiences: A Systematic Review to Improve Their Mental Well-being2025
  3. 3The Psychological Impact of In Vitro Fertilization (IVF): A Gender Systematic Review2026
  4. 4Factor Influencing Psychological Aspect among Women Undergoing in Vitro Fertilization or Intra Cytoplasmic Sperm Injection Cycles2024
  5. 5Assessment of Anxiety and Stress Levels among Women Undergoing In vitro Fertilization Treatment: An Observational Study2026