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July 30, 2025Indonesian Journal of Obstetrics and GynecologyOpen Access

Emotional Impact of In Vitro Fertilization (IVF): Anxiety, Depression, and Their Relationship with Pregnancy Outcomes

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Authors

FAFeranindhya AgianandaRNRaden Muharram NatadisastraNANurmiati Amir

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Overview

Cohort study shows increasing anxiety and depression in women undergoing IVF, indicating the need for mental health support.

Key Points

  • This research aims to explore the psychological effects of IVF, specifically anxiety and depression, and their relationship with pregnancy outcomes.
  • Cohort study conducted at Dr. Cipto Mangunkusumo General Hospital and Dr. Sander B. Daya Medika Clinic.
  • Data collected through questionnaires assessing anxiety, depression, and pregnancy outcomes during IVF.
  • Statistical analysis used Chi-square, Fisher’s exact test, and Friedman ANOVA for longitudinal data.
  • 61 participants completed the IVF process and associated evaluations.
  • Anxiety levels increased significantly during IVF (p < 0.001).
  • Depression levels also rose throughout IVF (p = 0.001).
  • No significant association was found between anxiety/depression scores and pregnancy outcomes (p > 0.05).

Cite This Study

Agiananda et al. (2025) studied this question.

synapsesocial.com/papers/69255726c0ce034ddc35a330https://doi.org/10.32771/inajog.v13i3.2626
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Assessment of Anxiety and Stress Levels among Women Undergoing In vitro Fertilization Treatment: An Observational Study2026
  2. 2Pregnancy and psychoemotional state of women after in vitro fertilization2024
  3. 3Effects of in vitro fertilization and intracytoplasmic sperm injection treatment on female patients' perinatal mental health: systematic review and meta-analysis2025
  4. 4Anxiety and perceptive functioning of infertile women during in-vitro fertilization: exploratory survey of an Italian sample.1999
  5. 5Factor Influencing Psychological Aspect among Women Undergoing in Vitro Fertilization or Intra Cytoplasmic Sperm Injection Cycles2024