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September 27, 2025AnesthesiologyOpen Access

The Enduring Table 1 Fallacy: A Meta-Research Study of Baseline Testing in Anesthesiology and Pain Trials

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Authors

ACAlessandro De CassaiBDBurhan DostETEsra Turunç

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Overview

Meta-research study uncovers widespread baseline testing in anesthesiology and pain trials, highlighting potential misinterpretations.

Key Points

  • Statistical testing of baseline characteristics remains prevalent in anesthesiology RCTs despite guidelines.
  • Among 2453 RCTs studied, 48.3% reported such testing, with only 19.2% showing significant differences.
  • Larger author teams reduced the odds of baseline testing, indicating a potential misunderstanding of randomization.
  • Education and improved editorial policies are crucial for aligning trial reporting with best practices.

Cite This Study

Cassai et al. (2025) studied this question.

synapsesocial.com/papers/68d7b3d4eebfec0fc5236476https://doi.org/10.1097/aln.0000000000005776
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