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May 20, 2005Anesthesia & Analgesia

The Quality of Randomized Controlled Trials in Major Anesthesiology Journals

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Key result

Major anesthesiology RCTs average a ~44% quality score, driven by poor randomization and observer blinding.

Why the study?

Increased attention has been directed at the quality of randomized controlled trials and their reporting, with a need to identify specific areas for improvement in anesthesiology journals.

Population

All RCTs published between January 2000 and December 2000 in leading anesthesiology journals

Comparison

Assessment using a previously validated 14-item quality tool

Design

Systematic review of published RCTs

Authors

MGMary Lou V. H. GreenfieldARAndrew RosenbergMRMichael O Reilly

Discussion

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Member takes

Overview

Suboptimal 2000 RCT quality scores in anesthesia journals caution interpretation of findings; supports targeted CONSORT training to improve future trial reporting.

Study Design

Type

Systematic Review

Structured PICO

P
Population
All randomized controlled trials published in four leading anesthesiology journals between January and December 2000.
E
Exposure
Assessment using a previously validated 14-item tool associated with study quality
O
Outcome
Quality score for each article

The quality of reporting and conduct of RCTs in major anesthesiology journals requires significant improvement, particularly regarding randomization methodology, blinding, and sample size estimates.

Cite This Study

Greenfield et al. (2005) conducted a systematic review in Randomized controlled trials in anesthesiology. Quality assessment using a 14-item validated tool was evaluated on Overall mean weighted quality score. The overall mean weighted quality score of RCTs in major anesthesiology journals was 44%, with very low scores for randomization blinding (5%) and blinding observers to results (1%).

synapsesocial.com/papers/6aaf65004104dfdc38cea00dhttps://doi.org/10.1213/01.ane.0000150612.71007.a3
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Also Consider

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