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September 27, 2025Asian Journal of Organic Chemistry

Advances in Continuous‐Flow Synthesis of Nitrogen‐Containing Heterocycles Through Sequence Transformations in the Past Decade (2016–2025)

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Authors

YGYingying GuoZFZ. FuASAi‐Rong She

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Overview

This review evaluates recent advances in nitrogen-containing heterocycles synthesis using continuous-flow technology, suggesting innovative pathways.

Key Points

  • Continuous-flow technology enhances synthesis efficiency of nitrogen-containing heterocycles, and may improve production safety and scalability.
  • The review covers advances in sequence transformations involved in synthesizing various nitrogen-containing ring structures over the last decade.
  • Innovations combining continuous-flow with methods like heterogeneous catalysis significantly enrich the pathways for organic synthesis.
  • The study promotes continuous-flow methods, highlighting their potential to produce a diverse array of nitrogen-containing compounds and pharmaceuticals.

Cite This Study

Guo et al. (2025) studied this question.

synapsesocial.com/papers/68d7b3d4eebfec0fc52365eahttps://doi.org/10.1002/ajoc.202500614
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